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"For a limited time, you can TRY the remarkable weight loss formula that people are raving about…free* for 30 days."

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"You will lose a substantial amount of fat if you decrease the amount of fructose in your diet. But there is a much EASIER way to do it!

M. Gibson lost 15 pounds with Optimum Trim "I've been taking Optimum Trim for just a week and I've already lost 4 pounds! It's pretty amazing! I haven't changed my diet, nor have I been exercising at all. I do plan to make changes to both my diet and exercise regime and expect my results to be even better. I'm really happy with the results so far and plan to continue using Optimum Trim to lose those last 15 pounds.

Thanks Optimum Trim!"
- M. Gibson, Kaneohe, HI

Did You Know That Statistically Speaking No Matter How Much Weight You Lose, There Is A 95% Chance That You Will Gain It All Back?

Discover The Secret To Losing The Weight And Keeping It Off...

Are you one of the 95% who feels like there is something keeping you from having the body that you want?

Don’t beat yourself up, because it’s just not your fault... that something is called high fructose corn syrup (HFCS)!

Now there is no doubt you want to lose weight, there is no question about that. But if you’re one of the 95% who’s gained all the weight back from previous diets, there are some facts you need to know about HFCS.

Fructose may be the biggest cause of obesity in the United States today. That's because in our fast-paced world, we want to eat in the quickest way possible. Fast food restaurants, donut and coffee shops make it easy to satisfy a hungry stomach on the go. We get into the habit of stopping for food, and we make our choices without thought; after all, we're already concentrating on driving in traffic, getting where we need to go next, and talking on our cell phones. Who has time to consider calories, or nutritional content? So we grab the most appealing item on the menu.

Unfortunately, all of these are made with inexpensive, easy-to-add corn-based syrups. Great for manufacturer's budget, but hard on the waistline.

Worst yet, if you visit any supermarket you will find most of the healthy items located around the perimeter of the store. If you drift down one of the center aisles instead, which is the way most of us shop, you’re doomed to a cart filled with cookies, soft drinks and ice cream. And almost all of these products contain large amounts of HFCS.

Here’s the facts –

Over the last thirty years, there has been an approximate 40% drop in the use of cane and sugar beet sweetener per person…and a 300% increase in the use of HFCS per person…And the majority of calories in the modern, industrial diet now come from sugar and complex carbohydrate sources!

Here’s a quote from the American Journal of Clinical Nutrition:

"...evidence that a marked increase in the use of HFCS, and therefore in total fructose consumption, preceded the obesity epidemic and may be an important contributor to this epidemic in the United States."*

FIGURE 1. Estimated intakes of total fructose (•), free fructose ({blacktriangleup}), and high-fructose corn syrup (HFCS, {diamondsuit}) in relation to trends in the prevalence of overweight ({blacksquare}) and obesity (x) in the United States.

In a nut shell here’s why HFCS causes you to store fat-

When you eat fructose, it literally bypasses a host of biochemical reactions needed to regulate food and appetite intake. Unlike glucose, fructose does not stimulate insulin production in the pancreas, and because of this cannot provide "satiety" signals to the brain.

If you find yourself always at the refrigerator door, you can thank HFCS for this.

Insulin also increases the hormone leptin. Leptin has been found to inhibit food intake. People lacking leptin are massively obese! Since fructose does not stimulate insulin production, lower than average levels of leptin would be seen after ingesting fructose. Obviously this is not good.

So What Are Your Options?

Of course nothing can replace a sensible diet and exercise program. And the ideal solution would be to simply cut out all processed foods. But that may be a bit impractical for most -and it certainly is not realistic. We all know what to do; we just don't seem to have the time to get it done.

Luckily, there is a new product specifically designed to help. It will:

  • Target fructose utilization
  • Kick start your metabolism
  • Prevent fat from receiving a one-way ticket to your waist line

and...

You heard about it here FIRST!

Introducing Optimum TrimTM, The Revolutionary New Weight Loss Supplement That Blocks Fructose Utilization For The Formation Of Fat.

No more starvation diets. No cutting out your favorite foods. No severe food cravings. No counting calories. Fat burned from all your problem areas.


How does Optimum TrimTM make this possible?

The main active ingredient in Optimum TrimTM is an all new natural compound called Ribolene, which is derived from the roots of Scutellaria baicalensis, commonly referred to as Chinese skullcap and Heartwood of Acacia catechu, known as “Black catechu” in India.

Ribolene works by substantially decreasing two key obesity markers TNFa and IL-6 circulating in the blood stream. These two cytokines are expressed in high levels in the chronically obese. Ribolene has been shown to significantly decrease both of these obesity markers by inhibiting fat conversion from fructose pathways and down-regulating PPAR gene expression (fat accumulation) and up-regulating PPARa (fat breakdown) protein. To a lesser extent there is also a moderate down-regulation of lipoprotein lipase (which breaks down fat) on the gene level.

Scientists at JSS Medical Research, Inc., in Montreal, Canada conducted a double blind clinical study that showed subjects taking Ribolene found in Optimum TrimTM, lost on average an astounding seven percent of their total body weight, compared to zero pounds lost for those who didn’t get this natural compound.

The participants in the study were between the ages of 40-75...typically the age group that has the most difficult time losing fat.

Participants were not given any advice on diet or physical activity. One can only imagine their results if they combined a sensible diet plan with a regular exercise program.

But We Didn’t Stop There… Optimum TrimTM also works through three additional pathways

Thermogenesis

Thermogenesis is the process of heat or energy production by the body through many biochemical and metabolic events.

The body accomplishes this when it’s metabolic rate rises above normal levels. This rise in metabolic rate is referred to as the thermogenic effect. There are basically three types of thermogenesis: Exercise, Cold and Diet –induced thermogenesis (food and dietary supplementation).

Dietary supplements which are used to arouse a thermogenic response are called thermogenic agents. Ephedra is a well known thermogenic agent but with potentially harmful side effects.

Optimum TrimTM contains four powerful thermogenic agents without the risk factors of ephedra, and with potentially more “firepower”.

  • Green Tea - Studies show that green tea can increase thermogenesis by up to 43% in a typical sedentary man! Another study showed that men taking green tea extract burned 266 more calories per day than did those in the placebo group.
  • Cayenne also known as Capsaicin - Animal and human studies show that Capsaicin increases the body’s production of heat as well as helping regulate blood sugar levels.

Cayenne was made famous by Beyonce, who recently used cayenne to help her lose 20 pounds for her role in the movie, "Dreamgirls".

  • Caffeine - Is a natural diuretic that helps rid the body of extra water held right under the skin. Even with low body fat, subcutaneous water can make the body appear puffy. Optimum TrimTM has just the right amount of caffeine to get the job done.
  • Evodamine - Has similar characteristics to Capsaicin in that it also increases heat production, as well being a highly effective appetite suppressant.

Thyroid Support

  • Guggulsterones - Aids in the support of thyroid hormones T3 and T4. When the body senses a reduction in calories, there’s also a corresponding reduction in the conversion of the thyroid hormone T4 intoT3. This slows down the metabolism. Guggulsterones stimulate T3 production and boosts the metabolism.

In one study, test subjects given guggulsterones lost 3 times more fat compared to the participants using diet and exercise alone. Over a six-week period, the group using guggulsterones lost 9.5 pounds of fat compared to 3.1 pounds for the group that just followed the diet and exercise program.

Appetite Suppressants

  • Cassia - Has been shown in studies to safely and effectively lower fasting glucose concentrations in people with type 2 diabetes. Low glucose levels are key to keeping blood sugar levels stable.
  • Gymnema - Also known as the “sugar killer” has been found in some studies to curb one’s desire for sweets, as well as reducing blood sugar and cholesterol levels.

This one two punch helps to keep blood sugar levels stable.

As you can see, we did not leave a fat burning stone unturned.

Optimum Trim's revolutionary weight loss formula:

  • Targets fructose metabolism which makes it difficult for those useless fructose calories to find their way to your hips, thighs, waist and buttocks.
  • Curbs your appetite so you won’t find yourself at the refrigerator bingeing on late night snacks.
  • Safely jump starts your metabolism and rockets fat loss without extreme dieting or intense workouts.
  • Skyrockets your body’s energy levels so you can enjoy your new active lifestyle.

But Don't Take Our Word For It. Here Are A Few More Clinical Studies That Show How Effective The Ingredients In Optimum TrimTM Are


A.*From a study published March 31, 1999 in the American Journal Of Clinical Nutrition

“If, as generally accepted, thermogenesis contributes 8-10% of daily EE in a typical sedentary man (760-950 kJ in our subjects), this 4% increase in 24-h EE (328 kJ) due to the green tea extract would extrapolate to a 35-43% increase in the thermogenesis compartment of daily EE.”

“In conclusion, oral administration of the green tea extract stimulated thermogenesis and fat oxidation and thus has the potential to influence body weight and body composition via changes in both EE and substrate utilization.”

Abdul G Dulloo, Claudette Duret, Dorothée Rohrer, Lucien Girardier, Nouri Mensi, Marc Fathi, Philippe Chantre and Jacques Vandermander.American
Journal of Clinical Nutrition, Vol. 70, No. 6, 1040-1045, December 1999

Note: EE = Energy Expenditure

From a study published in the Medicine & Science in Sports & Exercise:Volume 31(5) Supplement May 1999p S121

“The purpose of this study was to determine the effects of a guggalsterone extract-phosphate salt compound on body composition, plasma lipid levels, and mood states in overweight hyperlipidemic adults. In a double-blind, randomized, placebo-controlled fashion, 20 subjects with a body mass index (BMI) >25 were divided into three groups: Group A received 750 mg guggalsterones and 1,650 mg phosphate daily; Group B received a maltodextrin placebo; Group C received nothing (control) for six weeks. Subjects were instructed to follow an American Heart Association Step One Diet and a three day per week circuit exercise program supervised by an exercise physiologist. Body weight decreased significantly only for group A (-3.14%; p<0.05). All groups lost a significant amount of body fat; moreover, the magnitude of loss for group A was double that of either B or C (A, -3.8%; B, -1.8%, C -1.8%; p<0.01). In terms of actual fat weight lost, both group A (-4.3 kg) and C (-1.4 kg) lost a significant amount of fat weight (p<0.01). Again, the magnitude of fat lost for group A was three times that of group C. Profile of Mood States (POMS) fatigue decreased significantly for group A only (p <0.05) while vigor also increased significantly in group A by 14% (p <0.01). In conclusion, the guggalsterone-phosphate salt based product improved mood states in these overweight individuals, with more favorable body composition changes occurring in group A.”

Note: -4.3 kg equates to -9.46 pounds!

EFFECTS OF A GUGGALSTERONE EXTRACT-PHOSPHATE SALTS BASED PRODUCT ON BODY COMPOSITION IN OVERWEIGHT ADULTS [Annual Meeting Abstracts]

Kalman, D.; Colker, C. M.; Antonio, J.; Torina, G. C.; Brink, W. D.; Shi, Q.
Peak Wellness, Greenwich CT, Greenwich Hospital, Greenwich, CT, University of Nebraska-Kearney, Brink Consulting Group, Newton, MA, North Shore University Hospital, Manhasset, NY

Effects of red pepper on appetite and energy intake

“Two studies were conducted to investigate the effects of red pepper (capsaicin) on feeding behaviour and energy intake. In the first study, the effects of dietary red pepper added to high-fat (HF) and high-carbohydrate (HC) meals on subsequent energy and macronutrient intakes were examined in thirteen Japanese female subjects. After the ingestion of a standardized dinner on the previous evening, the subjects ate an experimental breakfast (1883 kJ) of one of the following four types: (1) HF; (2) HF and red pepper (10 g); (3) HC; (4) HC and red pepper. Ad libitum energy and macronutrient intakes were measured at lunch-time. The HC breakfast significantly reduced the desire to eat and hunger after breakfast. The addition of red pepper to the HC breakfast also significantly decreased the desire to eat and hunger before lunch. Differences in diet composition at breakfast time did not affect energy and macronutrient intakes at lunch-time. However, the addition of red pepper to the breakfast significantly decreased protein and fat intakes at lunch-time.”

“In Study 2, the effects of a red-pepper appetizer on subsequent energy and macronutrient intakes were examined in ten Caucasian male subjects. After ingesting a standardized breakfast, the subjects took an experimental appetizer (644 kJ) at lunch-time of one of the following two types: (1) mixed diet and appetizer; (2) mixed diet and red-pepper (6 g) appetizer. The addition of red pepper to the appetizer significantly reduced the cumulative ad libitum energy and carbohydrate intakes during the rest of the lunch and in the snack served several hours later. Moreover, the power spectral analysis of heart rate revealed that this effect of red pepper was associated with an increase in the ratio sympathetic : parasympathetic nervous system activity. These results indicate that the ingestion of red pepper decreases appetite and subsequent protein and fat intakes in Japanese females and energy intake in Caucasian males. Moreover, this effect might be related to an increase in sympathetic nervous system activity in Caucasian males.”

Authors: Yoshioka M. 1; St-Pierre S. 1; Drapeau V. 1; Dionne I. 1; Doucet E. 1; Suzuki M. 2; Tremblay A.*
Source: British Journal of Nutrition, Volume 82, Number 2, 1999 , pp. 115-123(9)

Combined effects of red pepper and caffeine consumption on 24 h energy balance in subjects given free access to foods

“The effects of red pepper and caffeine ingestion on energy and macronutrient balances were examined in eight Caucasian male subjects. All subjects participated in two randomly assigned conditions: control and experimental (red pepper and caffeine). After ingesting a standardized breakfast, subjects ate three meals ad libitum (lunch, dinner and breakfast) and snacks which were served approximately 2 h after the lunch and dinner over a 24 h period. Two appetizers (2×322 kJ with or without 3 g red pepper) were given before lunch and dinner, and a drink (decaffeinated coffee with or without 200 mg caffeine) was served at all meals and snacks except for the after-dinner snack. It is also important to note that on the experimental day, 8·6 and 7·2 g red pepper were also added to lunch and dinner respectively. Red pepper and caffeine consumption significantly reduced the cumulative ad libitum energy intake and increased energy expenditure. The mean difference in energy balance between both conditions was 4000 kJ/d. Moreover, the power spectral analysis of heart rate suggested that this effect of red pepper was associated with an increase in sympathetic:parasympathetic nervous system activity ratio. These results indicate that the consumption of red pepper and caffeine can induce a considerable change in energy balance when individuals are given free access to foods.”

Authors: Yoshioka M.; Doucet E.; Drapeau V.; Dionne I.; Tremblay
Source: British Journal of Nutrition, Volume 85, Number 2, February 2001 , pp. 203-211(9)

I'm Sure You'll Agree, Optimum TrimTM May Be The Most Potent Natural Weight Loss Formula Available

It doesn't matter if this is your first or twenty-fifth attempt at losing weight.

It doesn't matter if you’re twenty pounds or a hundred and twenty pounds overweight.

If you can swallow a pill in the morning and a pill in the evening, you will be amazed at what your body will look like after a month.

Imagine how much weight you could lose with the fat burning firepower Optimum TrimTM synergistically combines into one pill.

If you are serious about changing the way you look in as little as 30 days…you need Optimum TrimTM.

Sure, you could keep on doing things the way you’ve done them for years…but why put yourself through it? You and I both know the “old” ways of trying to lose weight just don’t cut it any more.

Optimum TrimTM will give you the best shot at:

  • Having the beach body you’ve always wanted.
  • Fitting into those sexy clothes you see while window-shopping.
  • Doing the fun things you only see ‘skinny’ people doing because they’re in great physical shape.
  • Boosting your confidence and self-esteem.
  • Taking control of your life.

This is YOUR time…YOUR chance…YOUR opportunity…to change YOUR life.

Optimum TrimTM will give you that chance.

P.S. We put everything but the kitchen sink into Optimum Trim’s incredible fat busting formula. As you can imagine it is not cheap to produce. In fact, it costs roughly 40% more to manufacture Optimum TrimTM than your typical average weight loss supplement. Optimum TrimTM is far from average.

This is why you will NOT find Optimum TrimTM in any retail stores. You'd easily pay well over a hundred dollars for just one bottle!

But we want you to save as much money as possible, so we cut out the middle-man and you can get it directly from the source…US!

And although Optimum TrimTM costs a lot more to manufacture than your average weight loss supplement, AND...is worth every bit paying over a hundred dollars for...you get the special low VIP member price after the 30-day trial period!

P.P.S. Oh yeah...one more thing. We really want to keep prices down, so we ship Optimum TrimTM in a “no-frills” package. No fancy packaging here. If you want that, we don’t have it.

 
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    Frequently Asked Questions

    1. How safe is Optimum TrimTM
    2. When will I see results? How long can I stay on Optimum TrimTM?
    3. Won't Optimum TrimTM block the absorption of vitamins and minerals of fruits and vegetables?
    4. Is Optimum TrimTM safe for children?
    5. Should I use Optimum TrimTM if I'm pregnant or nursing an infant?
    6. How Long will a bottle of Optimum TrimTM last me?
    7. Can I take Optimum TrimTM with my prescription drugs?
    8. Will Optimum TrimTM work without a diet or exercise program?
    9. What is your shipping policy?
    10. Do you ship outside the U.S.?
    11. Is Optimum Trim guaranteed?
    12. What are the terms and conditions of the free trial offer?
    13. Is there a limit to the free trial offer?

    Q: How safe is Optimum TrimTM?
    Optimum TrimTM contains only natural ingredients that are safe to take. The caffeine in Optimum TrimTM is very small. It is always wise to consult with your physician if you have a concern.

    Q: When will I see results? How long can I stay on Optimum TrimTM?
    Of course everyone is different, but you should see results after the first 7-10 days. Optimum TrimTM works extremely well, but for health reasons, try not to lose weight too quickly. Optimum TrimTM is safe to take long term, but always check with your physician if you have a concern.

    Q: Will Optimum TrimTM block the absorption of vitamins and minerals from fruits and vegetables?
    No. Optimum TrimTM does not work the same way as the fat blocking diet products on the market such as Olestra. In a four-week study conducted in Holland, 3 gm/day (equivalent to just 6 potato chips) of sucrose polyester (the general name for olestra-like chemicals) caused a 20% decline in beta-carotene levels and a 38% decrease in lycopene, another key carotenoid (Am. J. Clin. Nutr. 62:591 (1995)). There are numerous studies about the malnutrition effects of these types of diet products because they interfere with the fat soluble vitamins A, K, D and E, all a key to nutritional status.

    Q: Is Optimum TrimTM suitable for children?
    Optimum TrimTM is NOT designed for children.

    Q: Should I use Optimum TrimTM if I’m pregnant or nursing an infant?
    No.

    Q: How long will a bottle of Optimum TrimTM last me?
    Each bottle of Optimum TrimTM contains 60 pills, which is a 30-day supply.

    Q: Can I take Optimum TrimTM with my prescription drugs?
    Always consult your physician before taking any new supplement.

    Q: Will Optimum TrimTM work without an exercise or diet program?
    Optimum TrimTM is truly a one-of-a-kind weight loss supplement that has no peers. However, it is not a ‘miracle pill’. You should incorporate a sensible diet and exercise program into your daily regimen to achieve best results. However, we do not recommend taking either to extremes. This can be counterproductive to your weight loss goals, as well as being unhealthy for you.

    Q: What is your shipping policy?
    Our basic shipping and handling charges are $6.95. We also ship Internationally except to Canada and Australia.

    Q: Do you ship outside the U.S.?
    We ship anywhere in the world except to Canada and Australia. All other countries will incur a $27.95 shipping charge.

    Q: Is Optimum Trim guaranteed?
    Optimum Trim comes with a 90-day Satisfaction Guarantee. What this means is that anytime up to 90 days after purchasing if you aren't 100% satisfied with our product, you can return any unused portion of Optimum Trim for a 100% refund*, no questions asked (not for use with VIP Program). Note: your return package must be received by our Receiving Department within 90 days from the shipped date to receive a refund. If you have enrolled in our VIP Program please refer to the Terms and Conditions of the VIP Program for your guarantee. (All shipping fees are non-refundable. Terms and conditions of refund apply*)

    Q: What are the terms and conditions of the free trial offer?
    Terms & Conditions: Just cover shipping and handling of $6.95 (International $27.95) to start your FREE trial now and receive a one-month supply of Optimum TrimTM (retails for $69.95). You'll have until June 15, 2008 to evaluate the product and see the results for yourself. If you enjoy Optimum TrimTM, simply do nothing. You will be billed the super low price of $59.95 at the end of your 30-day trial period...a 15% savings! Plus, when you accept this trial, you will also received a FREE membership in the Optimum TrimTM VIP program. That means that you'll continue to get a fresh one-month supply of Optimum TrimTM every 30 days from your original order for the low price of $59.95 (+ $6.95 shipping and handling - International $27.95)... a 15% discount! If, for ANY reason, you decide that Optimum TrimTM is not for you, simply return the unused portion within 30 days of the placement of your trial order. You will NEVER be billed. You may cancel at anytime. Please send returns to:

    Biodynamic Laboratories LLC
    Returned Merchandise
    11701 East 53rd Ave
    Denver, CO 80239

    Q: Is there a limit to the free trial offer?
    Yes, limit one free trial per household.

    If you still have questions, please use the convenient form below to email us.

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    The statements made in this promotion have not been evaluated by the Food & Drug Administration. (The FDA only evaluates foods and drugs, not supplements like these products.) This product is not intended to diagnose, prevent, treat, or cure any disease. As individuals differ, so will their results.

    REFERENCES

    Diabetes Care. 2003 Dec;26(12):3215-8 Cinnamon improves glucose and lipids of people with type 2 diabetes. Khan A, Safdar M, Ali Khan MM, Khattak KN, Anderson RA. Department of Human Nutrition, NWFP Agricultural University, Peshawar, Pakistan. | Eur J Clin Invest. 2006 May;36(5):340-4, Effects of a cinnamon extract on plasma glucose, HbA, and serum lipids in diabetes mellitus type 2. Mang B, Wolters M, Schmitt B, Kelb K, Lichtinghagen R, Stichtenoth DO, Hahn A. Nutrition Physiology and Human Nutrition Unit, Institute of Food Science, University of Hannover, Hannover, Germany. | J Ethnopharmacol. 1990 Oct;30(3):295-300, Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients.Baskaran K, Kizar Ahamath B, Radha Shanmugasundaram K, Shanmugasundaram ER. Department of Biochemistry, Postgraduate Institute of Basic Medical Sciences Madras, India.| Diabetes Res Clin Pract. 1990 May-Jun;9(2):143-8, Okabayashi Y, Tani S, Fujisawa T, Koide M, Hasegawa H, Nakamura T, Fujii M, Otsuki M. Second Department of Internal Medicine, Kobe University School of Medicine, Japan. | J Ethnopharmacol. 1990 Oct;30(3):265-79, Possible regeneration of the islets of Langerhans in streptozotocin-diabetic rats given Gymnema sylvestre leaf extracts. Shanmugasundaram ER, Gopinath KL, Radha Shanmugasundaram K, Rajendran VM. Department of Biochemistry, University of Madras, India. | American Journal of Clinical Nutrition, Vol. 81, No. 1, 122-129, January 2005 Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men. Tomonori Nagao, Yumiko Komine, Satoko Soga, Shinichi Meguro, Tadashi Hase, Yukitaka Tanaka and Ichiro Tokimitsu | American Journal of Clinical Nutrition, Vol. 70, No. 6, 1040-1045, December 1999 Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Abdul G Dulloo, Claudette Duret, Dorothée Rohrer, Lucien Girardier, Nouri Mensi, Marc Fath, Philippe Chantre and Jacques Vandermander | Am J Physiol Regul Integr Comp Physiol 292: R77-R85, 2007.Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea Kristel Diepvens, Klaas R. Westerterp, and Margriet S. Westerterp-Plantenga. Department of Human Biology, Maastricht University, Maastricht, The Netherlands | Combined effects of red pepper and caffeine consumption on 24 h energy balance in subjects given free access to foods Authors: Yoshioka M.; Doucet E.; Drapeau V.; Dionne I.; Tremblay A. Source: British Journal of Nutrition, Volume 85, Number 2, February 2001 , pp. 203-211(9) | Effects of red pepper on appetite and energy intake. Authors: Yoshioka M. St-Pierre S. Drapeau V. Dionne I. Doucet E. Suzuki M. Tremblay A. Source: British Journal of Nutrition, Volume 82, Number 2, 1999 , pp. 115-123(9) | EFFECTS OF A GUGGALSTERONE EXTRACT-PHOSPHATE SALTS BASED PRODUCT ON BODY COMPOSITION IN OVERWEIGHT ADULTS. Medicine & Science in Sports & Exercise. 31(5) Supplement:S121, May 1999.
    Kalman, D. 1; Colker, C. M. 2; Antonio, J. 2; Torina, G. C. 1; Brink, W. D. 4; Shi, Q. 5 | Singh K, Chander R, Kapoor NK. (1997). Guggulsterone, a potent hypolipidaemic, prevents oxidation of low density lipoprotein. Phytotherapy Research, 11, 291-294 | Rosenbaum, M., Hirsch, J., & Leibel, R.L. (2000). Effects of changes in body weight on carbohydrate metabolism, catecholamine excretion, and thyroid function. American Journal of Clinical Nutrition, 71, 1421-1432Planta Med. 2001 Oct;67(7):628-33. Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist. Kobayashi Y, Nakano Y, Kizaki M, Hoshikuma K, Yokoo Y, Kamiya T.

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    Why Optimum Trim Works

    The secret is in Optimum TrimTM's proprietary formula. Never before has a weight loss supplement effectively addressed weight loss from these four key areas:

    1. Fructose metabolism
    2. Thermogenesis
    3. Thyroid support
    4. Appetite suppressant

    The crown jewel of this formula is the active ingredient Ribolene.

    Ribolene is a natural anti-oxidant that substantially decreases two cytokines TNFa and IL-6 circulating in the blood stream. These two cytokines are expressed in high levels in the chronically obese subjects. Ribolene has been shown to blunt meal response to fructose and inhibiting fat conversion from fructose, by a down regulated fructose metabolism pathway less gene expression of fructokinase and aldolase. Ribolene significantly up-regulates both GLUT4 and PDK4 gene expressions in muscle that may associate with more up taking glucose and more fatty acid burns by muscle.

    Testimonials

    "This year I plan on keeping my New Year's resolution and taking off the weight I have put on over the last 2 years, 100 pounds, I've tried other weight loss products with no success or ended up with the jitters and shakiness, since I started the Optimum Trim regiment there have been no side effects and the weight is still coming off. I haven't really changed my diet, but have added a daily walking routine to my schedule. If the success I have had since starting Optimum Trim continues i will stay with it until all 100 pounds have been shed. My doctor has even been surprised that for the first time in 2 years instead of a gain in my weight last month I had lost 11 pounds...in just 6 days!
    Stewart Rose
    Los Angeles, CA

    "It's been one week since I started taking Optimum Trim and I've already lost 3 pounds! That may not seem like a lot, but there were some days that I didn't eat all that great. I've taken many diet products before, but this is the only one that doesn't make me feel jittery. I have a lot more energy throughout the day and I don't have any food cravings. I love this product! Thank you Optimum Trim!"
    Kenneth Paul
    Los Angeles, CA

    "I have been trying to lose those final 10 pounds for the last decade or so, but have been unsuccessful. I exercise regularly and try to eat sensibly, but it's been eluding me. I've tried other diet supplements but I felt like my heart was racing and some even made me feel ill, so I discontinued their use. I was a bit skeptical about trying another one, but I'm so happy I did. I've been taking Optimum Trim for 2 weeks now and have lost 4 pounds, without changing my diet or exercise program. I don't have any negative side effects. In fact I have a lot more energy and I don't feel like snacking. I'm finally on my way to reaching my goal. Thank you!
    Anne Miyata
    Honolulu, Hawaii

    I received my bottle of Optimum Trim on the 19th and it is now 7 days later...These are the best weight loss supplements I've had by far! They give me a nice long lasting wave of energy as opposed to a burst and then a crash like most products containing caffeine or something similar. I now have the energy to get through a full day of work and hit the gym in the evening. Also, I am very sensitive to caffeine but Optimum Trim did not make me feel bad at all. I find that it takes less food to fill me up and I'm even craving more healthy foods unlike before. I highly recommend this product to ANYBODY stuck in a rut."
    Erica Hughes
    Van Nuys, CA